Over-the-counter pain relievers These include Adderall XR acetaminophen (Tylenol) and noncopyrightal anti-inflammatory drugs (NSAIDs) like aspirin, ibuprofen (Advil, Motrin), and naproxen (Aleve, Naprosyn). NSAIDs can reduce fever and pain, and swelling from arthritis or muscle sprains. However, they can cause stomach upset or ulcers in some people